| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3467185 | European Journal of Internal Medicine | 2008 | 5 Pages |
Abstract
The co-occurrence of parathyroid hyperplasia with pancreatic endocrine tumours and/or pituitary adenoma is classified as Multiple Endocrine Neoplasia type 1 (MEN-1) and is caused by a germ-line mutation in MEN-1 gene encoding a tumour suppressor protein, menin. This review presents clinical expressions, diagnosis and management of the MEN-1 syndrome. Properties and mechanisms of menin functions are also reviewed.
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Authors
Grzegorz Piecha, Jerzy Chudek, Andrzej Więcek,