Geriatric assessment and chronic kidney disease in the oldest old: The Octabaix study

BackgroundThe prevalence of chronic kidney disease (CKD) in older people is increasing.We determine the proportion of CKD in a sample of 321, 85-year-old community-dwelling subjects, and assess the association of socio-demographic data, global geriatric assessment data and comorbidity with CKD according to the estimated glomerular filtration rate (eGFR) of subjects.MethodsSerum creatinine, eGFR (derived in ml/min/1.73 m2 using the Modification of Diet in Renal Disease formula), socio-demographic variables, the Barthel Index (BI), the Spanish version of the Mini-Mental State Examination (MEC), the Mini Nutritional Assessment (MNA), the Charlson Index, the Gait Rating Scale, social risk, quality of life and prevalent chronic diseases were collected.ResultsCKD prevalence was 56.7% for eGFR < 60 ml/min/1.73 m2, 19.9% for eGFR < 45 ml/min/1.73 m2 and 6.6% for GFR < 30 ml/min/1.73 m2. Multiple logistic regression analysis showed that a prior diagnosis of hypertension was associated with an eGFR < 60 ml/min/1.73 m2 (p < 0.008, OR 2.134, 95% CI 1.216–3.744). A diagnosis of heart failure (p < 0.001, OR 3.610, 95% CI 1.677–7.771) and a poor score on the quality of life measure (p < 0.008, OR 0.9660, 95% CI 0.966–0.995) were associated with an eGFR < 45 ml/min/1.73 m2.ConclusionsMore than half of the oldest old in this study had an eGFR < 60 ml/min/1.73 m2. A history of hypertension was associated with CKD. The group of patients with an eGFR < 45 ml/min/1.73 m2 was associated with a diagnosis of heart failure and a worse quality of life.