Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3474695 | Italian Journal of Medicine | 2012 | 6 Pages |
Abstract
In most cases, iloprost is administered in a single cycle of treatment over 5 days at 1-2 ng/kg/min for 6Â hours/day, but no research has investigated the effectiveness of early retreatment after the first cycle results in only a partially response. Only a few studies examining small numbers of patients have evaluated iloprost in AVN/BME, preferring, in most cases, the dose of 1 ng/kg/min and obtaining clinical improvement both in BME and in AVN in times comparable to surgical core decompression. This case report demonstrates the safety and effectiveness of early repetition of the maximal dose of iloprost before BME evolves into AVN, as well as in cases initially appearing serious and requiring surgical procedures.
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Authors
Simone Meini, Grazia Panigada,