Article ID Journal Published Year Pages File Type
371206 Research in Developmental Disabilities 2015 11 Pages PDF
Abstract

•Challenging behavior, comorbid psychopathology, and AD/HD was investigated in FRAX.•Results revealed high levels of challenging behavior and AD/HD symptoms.•Challenging behavior and comorbid psychopathology were positively correlated.•Stereotypy correlated most strongly with comorbid psychopathology.•ASD predicted challenging behavior, and gender predicted AD/HD symptoms.

The present study sought to investigate the relationship between challenging behavior, comorbid psychopathology, and Attention-Deficit/Hyperactivity Disorder (AD/HD) in Fragile X Syndrome (FRAX). Additionally, this study sought to examine how such disorders are predicted by gender, presence of autism spectrum disorder (ASD), and presence of intellectual disability (ID). A total of 47 children and adolescents with FRAX were assessed. Results revealed high levels of challenging behavior and AD/HD symptoms within the sample, with some participants exhibiting symptoms of comorbid psychopathology. Further analysis revealed that challenging behavior and comorbid psychopathology were positively correlated, with stereotypy correlating most strongly with comorbid psychopathology. In addition, ASD was found to predict challenging behavior, and gender was found to predict AD/HD symptoms. The implications of these findings are discussed.

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