Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3802925 | Medicina Clínica | 2009 | 6 Pages |
Abstract
The results indicate that the aberrant methylation of the promoter region is an important event in carcinogenesis of gynecological tumors and that the pattern of gene methylation is associated with the nature of the tumor. These particular characteristics can deliver relevant information on the major metabolic pathways altered in each tumor type. In addition to complementary studies (ie, loss of expression and/or function), this represents a clinical tool for the proper management of the disease.
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Authors
Pamela Leal Rojas, Leonardo Anabalón RodrÃguez, Patricia GarcÃa Muñoz, Oscar Tapia Escalona, Pablo Guzmán González, Juan Carlos Araya Orostica, Miguel Villaseca Hernández, Juan Carlos Roa Strauch,