Article ID Journal Published Year Pages File Type
3805995 Medicine - Programa de Formación Médica Continuada Acreditado 2013 10 Pages PDF
Abstract
We begin this chapter by describing the recirculation of T lymphocytes and explaining how particular populations of T lymphocytes selectively enter lymph nodes and specific tissues, a phenomenon known as lymphocytic accommodation or addressing. We examine in detail differentiation following an antigen encounter, specifically the three functional states of T lymphocytes: virgin, memory and effector. We pay special attention to the effector functions of the helper and cytotoxic T lymphocytes, as well as their differentiation into Th1, Th2 and Th17 lymphocytes. Finally, we briefly examine the Tγδ and NKT lymphocytes as well as immunological memory and the shutdown of immune responses.
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