Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3806042 | Medicine - Programa de Formación Médica Continuada Acreditado | 2012 | 5 Pages |
Abstract
Venous thromboembolism (VTE) is the third most common cause of death from cardiovascular disease after heart attack and stroke. Sequelae after VTE include chronic pulmonary hypertension and post-thrombotic syndrome. The diagnosis of VTE is based on models of clinical probability, plasma D dimer and noninvasive imaging modalities (compression ultrasound or chest CT). Most patients will respond to anticoagulation with parenteral unfractionated heparin or low molecular weight heparins, followed by oral vitamin K antagonists (sintrom or warfarin) during 3-6Â months with coagulation monitoring of INR in the therapeutic range. Several novel oral anticoagulants are in development (dabigatran rivaroxaban, apixaban) which could replace vitamin K antagonists, since they are prescribed in fixed doses and do not need any coagulation monitoring.
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Authors
A. Alfonso Piérola, J.A. Páramo Fernández,