Article ID Journal Published Year Pages File Type
3809108 Medicine - Programa de Formación Médica Continuada Acreditado 2012 5 Pages PDF
Abstract
Hyperthyroidism is a clinical entity characterized by increased thyroid hormone production. The therapeutic approach differs according to the etiology, being the most common causes Graves' disease, toxic multinodular goiter and toxic adenoma; and according to patient characteristics. Antithyroid drugs (metimazole, carbimazole) inhibit the formation of thyroid hormones, and they can be used as definitive treatment in Graves' disease or to achieve normal thyroid function prior to treatment with 131I or surgery. Treatment with 131I can be used as a treatment for hyperthyroidism, sometimes requiring repeated doses for cure, with the main side effect of hypothyroidism. Total thyroidectomy may be the treatment of choice for toxic multinodular goiter and Graves disease, requiring later levothyroxine replacement therapy, may be more conservative in the toxic adenoma with subtotal thyroidectomy.
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