Article ID Journal Published Year Pages File Type
3822148 La Presse Médicale 2014 8 Pages PDF
Abstract

SummarySystemic lupus erythematosus is a prototypic but heterogeneous autoimmune disease. The major clinical symptoms and signs are reviewed, as well as the main immunological abnormalities. Emphasis is put on the role of long-lived autoimmune plasma cells, not affected by current immunosuppressants and biologics, which are responsible for refractoriness and relapses.

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