| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3830572 | Revista Médica Clínica Las Condes | 2012 | 6 Pages |
ResumenIntroducciónLas dislipidemias son un problema emergente en pediatría, por sus consecuencias a largo plazo; no se conocen cifras actuales de escolares y adolescentes sanos en nuestro medio.ObjetivosEstudiar las concentraciones de Iipidos séricos en escolares y adolescentes chilenos sanos.Pacientes y MétodosEn un estudio descriptivo transversal, entre 2010 y 2011. Se midieron 191 niños (5-16 años; niñas: 93; varones: 98), controlados en Clínica Las Condes y que corresponden a grupos socioeconómicos altos. Con un consentimiento escrito previo de padres y asentimiento de los niños, se registraron antecedentes, se tomó muestra de sangre y se les midió talla, peso y perímetro abdominal (PAb).ResultadosUn 29% reportó antecedentes familiares de enfermedad cardiovascular o diabetes. El IMC y PAb estaban en rangos normales. Entre 6 y 11 años, fueron comparables entre mujeres y varones: el colesterol total (CT) (169,1 ± 25,1 vs 165,2 ± 25,4 mg/dL(NS), LDL (101,1 ± 20,9 vs 96,5 ± 22,8 mg/dL (NS), triglicéridos (70,0 ± 26,4 vs 66,1± 31,8 g/dL; NS). El CT fue mayor en adolescentes (12-16 años) mujeres que en varones (179,1 ±23,7 vs 150,2 ± 28,5mg/dL; p< 0,001), lo mismo el LDL (104,4 ± 29,9 vs 83,9 ±22,6 mg/dL, p< 0,001). Presentaban valores aumentados (CT> 200 mg/dL) un 12% de mujeres y un 5% de varones (NS). Aquellos niños con lactancia materna (LM) < 3 m. presentaban CT mayor que los con LM ≥ 3m. (172, 9 ± 26,5 vs 163,1 ± 27,1; p< 0,025), sin relación con peso de nacimiento.ConclusionesEn niños y adolescentes chilenos sanos de estratos socioeconómicos altos, hay una alta proporción con colesterol total y colesterol LDL en zonas de riesgo o aumentadas. Las concentraciones de colesterol de adolescentes mujeres son significativamente mayores que las de varones. No se observó una asociación de lípidos séricos con perímetro abdominal o con IMC.
SummaryBackgroundIncreased serum lipids are one of the emergent public health problems in Pediatrics, associated to later consequences for the adult life. No recent information is available about serum lipids in healthy Chilean children and adolescents.ObjectivesTo assess serum lipids concentrations in healthy Chilean children and adolescents.Subjects and MethodsIn a descriptive and cross sectional study, 191 healthy children and adolescents (5-16 y), both gender, were evaluated between 2010 and 2011, in a private clinic in Santiago (Clínica Las Condes), attending to high socioeconomic groups. After a history and a written consent by parents and children, a blood sample was drawn. Weight, height, and abdominal circumference (AC) were also measured.ResultsFamiliar history of diabetes type II or cardiovascular disease was present in 29%. The BMI and AC were within normal limits. The total cholesterol (TC) among schoolchildren (6-11 y) was comparable between boys and girls: TC (169.1 ± 25.1 vs 165.2 ± 25.4 mg/dL (NS), LDL (101.1 ± 20.9 vs 96.5 ± 22.8 mg/dL (NS), and triglycerides (70.0 ± 26.4 vs 66.1± 31.8 mg/dL, NS). Between 12 and 16 y, the TC was higher in females than in males (179.1 ±23.7 vs 150.2 ± 28.5 mg/dL; p< 0.001), and also the LDL (104.4 ± 29.9 vs 83.9 ± 22.6 mg/dL, p< 0.001). As a whole, the rate of increased TC (> 200 mg/dL) was 12% in females and 5% in males (NS). Those children with history of breast feeding < 3mo. presented greater TC levels than the others (172.9 ± 26.5 vs 163.1 ± 27.1; p< 0.025).ConclusionsA significant rate of healthy children and adolescents present increased serum cholesterol levels. Adolescent girls present greater cholesterol levels than males. History of shortened breast feeding (< 3 mo.) was associated to increased cholesterol levels; no association among serum lipids and BMI or abdominal circumference was found.
