Sleep-Related Breathing Disorder and Heart Disease—Central Sleep Apnea

This article reviews cardiovascular physiology and ventilatory control during sleep, the epidemiology of sleep-related breathing disorder (SRBD) in congestive heart failure (CHF), the pathophysiology of central sleep apnea (CSA) as it relates to CHF, and the clinical features and implications of SRBD in systolic CHF. It then focuses on treatment options for CHF-related CSA including continuous positive airway pressure and newer modalities such as adaptive pressure support servo-ventilation.