Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3840176 | Translational Research | 2013 | 10 Pages |
Abstract
Telomeres are DNA-protein structures that cap the ends of chromosomes; telomerase is the enzyme that ensures their integrity. Telomere biology has recently been implicated in the pathogenesis of a variety of lung diseases, including idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease/emphysema, and lung cancer. This review highlights recent discoveries pertaining to the role of telomere biology in lung disease.
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Authors
John M. Gansner, Ivan O. Rosas,