Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3840750 | Translational Research | 2011 | 5 Pages |
Abstract
The mechanisms underlying alcohol-induced hepatic steatosis are complex, involving the disturbance of several signaling pathways. We have gained a better understanding of the role of the innate immune system in the liver and its effects on lipid metabolism and uncovered a number of circulating factors that can influence the response of the liver to ethanol. In this report, we will focus on the potential role of ceramide on AMP-activated protein kinase, as a mediator of alcohol-induced hepatic steatosis.
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Authors
Rodjawan Supakul, Suthat Liangpunsakul,