Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3847649 | American Journal of Kidney Diseases | 2014 | 8 Pages |
Abstract
Lower serum bicarbonate concentrations are associated independently with rapid kidney function decline independent of eGFR or albuminuria in community-living persons with baseline eGFR > 60 mL/min/1.73 m2. If confirmed, our findings suggest that metabolic acidosis may indicate either early kidney disease that is not captured by eGFR or albuminuria or may have a causal role in the development of eGFR < 60 mL/min/1.73 m2.
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Authors
Todd H. MD, Michael G. MD, MPH, Ronit DPhil, Leonard MD, Mark J. MD, MS, Andrew N. MD, PhD, David S. MD, MPH, Bryan MD, MS, Ian H. MD, MS, Joachim H. MD, MAS,