Effects of Modality Change and Transplant on Peak Oxygen Uptake in Patients With Kidney Failure

Vo2peak increases significantly after kidney transplant, but not with daily hemodialysis; this improvement reflects increased peak cardiac output through increased peak heart rate. Despite statistical significance, the increase in Vo2peak was not clinically significant, suggesting the need for interventions such as exercise training to increase Vo2peak in all patients regardless of treatment modality.