Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3851441 | American Journal of Kidney Diseases | 2009 | 10 Pages |
Abstract
Urinary KIM-1 level was increased in patients with nondiabetic CKD with proteinuria and decreased in parallel with proteinuria by using losartan, sodium restriction, their combination, losartan plus HCT, and the latter plus sodium restriction. These results are consistent with the hypothesis of amelioration of proteinuria-induced tubular damage. Long-term studies are warranted to evaluate whether targeting treatment on KIM-1 can improve outcomes in patients with CKD with proteinuria.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Nephrology
Authors
Femke MD, Vishal S. PhD, Harry PhD, Henri PhD, Kevin MD, Inge MD, PhD, Joseph V. MD, PhD, Liffert MD, PhD, Gerjan MD, PhD,