The Use of Neural Networks in Evaluation of the Direction and Dynamics of Changes in Lipid Parameters in Kidney Transplant Patients on the Mediterranean Diet

We concluded that the MD diet would be ideal for posttransplantation patients without serious pathologic dyslipidemia. In the case of patients with substantial dyslipidemia, appropriate pharmacologic treatment lowering proatherosclerotic lipid levels should be used in combination with the MD. Artificial neural networks (ANNs) were a useful tool in modeling biological parameters, showing dynamics of the studied interactions in a very detailed way. ANN is the most suitable method for investigations with many variables, interconnected nonlinearly; therefore, this method allows for a more general approach to biological problems. However, it should be noted that considerable data sets are required to obtain a satisfactory fit to the data. Moreover, to ensure the predictive power of this method for new cases, the representative database is indispensable. In spite of these demands, ANN is a prospective tool for reliable, quick assessments and predictions.