Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3859232 | The Journal of Urology | 2015 | 10 Pages |
Abstract
Given that BMP-7 has a critical role in renal injury repair and nephrogenesis, these findings show that cell specific changes in BMP-7 expression contribute to the onset of irreversible renal injury and impaired kidney development secondary to congenital urinary tract obstruction. Accordingly therapies that target these cell populations to restore BMP-7 activity may limit disease progression in patients with obstructive uropathy.
Keywords
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Nephrology
Authors
Scott R. Manson, Joseph B. Song, Qiusha Guo, Helen Liapis, Paul F. Austin,