| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3863460 | The Journal of Urology | 2014 | 9 Pages |
Abstract
KLF4 may function as a tumor suppressor gene in urothelial cancer since down-regulation of KLF4 by promoter hypermethylation would promote cancer progression. In addition, decreased expression of KLF4 or its promoter hypermethylation may have predictive value for early recurrence in patients with nonmuscle invasive bladder cancer.
Keywords
NMIBC5-Aza-dCRFSGAPDHTURBTKLF45-aza-2-deoxycytidineTransurethral resection of bladder tumorRecurrence-free survivalEMTGenesNonmuscle invasive bladder cancerTumor suppressorKrüppel-like factor 4Urinary bladderMortalitypolymerase chain reactionPCRCarcinomaepithelial-to-mesenchymal transitionglyceraldehyde-3-phosphate dehydrogenaseUrothelium
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Authors
Heng Li, Ji Wang, Wei Xiao, Ding Xia, Bin Lang, Tao Wang, Xiaolin Guo, Zhiquan Hu, Zhangqun Ye, Hua Xu,