| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3864891 | The Journal of Urology | 2013 | 9 Pages |
Abstract
Based on available data, Randall plaque formation is similar to extracellular matrix mineralization at many body sites. Renal interstitial collagen becomes mineralized, assisting plaque growth through the interstitium until the mineralizing front reaches papillary surface epithelium. Plaque exposure to pelvic urine may also be a result of reactive oxygen species triggered epithelial sloughing.
Keywords
NF-κBphagocytic oxidaseIαInuclear factor κ-light-chain-enhancer of activated B cellsOPNTHPNAGPKCAP-1MCP-1NADPHN-acetyl-β-glucosaminidaseROSOsteopontinOxalateInter-α-InhibitorOxidative stressPhoxlactate dehydrogenaseLDHNephrolithiasisnicotinamide adenine dinucleotide phosphateTamm-Horsfall proteinmonocyte chemoattractant protein-1activator protein 1Protein kinaseCaPCalcium oxalateKidneyReactive oxygen species
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Authors
Saeed R. Khan,