High Grade Primary Vesicoureteral Reflux in Boys: Long-Term Results of a Prospective Cohort Study

Baseline perfusion defects were seen on 99mTc-dimercapto-succinic acid scan at presentation in 115 of our 151 patients (76%) independent of presentation mode. New permanent defects developed in abnormal and previously normal kidneys, and were associated with urinary tract infection. Being circumcised was associated with fewer urinary tract infections and a lower incidence of observed new permanent defects (5.2% vs 10.2%).