Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3873022 | The Journal of Urology | 2010 | 8 Pages |
Abstract
Our results show the synergistic activity of interferon-α and sorafenib. These findings provided the rationale for combination therapy with interferon-α and sorafenib in patients with advanced renal cell carcinoma.
Keywords
PBSIFN-αPDGFβMetastatic RCCRCCCTLmRCCTreginterferon-alphaInterferon-αTILTumor infiltrating lymphocyteRegulatory T cellDendritic cellNatural killer cellRenal cellSorafenibcombination indexplatelet-derived growth factor-βinhibitory concentrationVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Phosphate buffered salinecytotoxic T lymphocyteAntineoplastic combined chemotherapy protocolsRenal cell carcinomaCarcinomafraction affectedKidney
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Authors
Ario Takeuchi, Masatoshi Eto, Katsunori Tatsugami, Hisakata Yamada, Toshihiro Oki, Keijiro Kiyoshima, Yasunobu Yoshikai, Seiji Naito,