Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3878207 | The Journal of Urology | 2008 | 8 Pages |
Abstract
The inhibition of 5α-reductase represents a valid target for prostate cancer risk reduction and treatment strategies. The greater suppression of dihydrotestosterone observed with agents that inhibit each 5α-reductase isoenzyme may translate into enhanced outcomes and studies are under way to test this hypothesis.
Keywords
Reduction by Dutasteride of Prostate Cancer EventsDHTPCPTPSA5αR5α-reductaseADIprostatic intraepithelial neoplasiaProstate specific antigenandrogenstransit amplifyingProstate Cancer Prevention TrialDihydrotestosteroneandrogen response elementProstatic neoplasmsAREBenign prostatic hyperplasiaBPHProstatePINreduceAndrogen Receptor
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Authors
Donald J. Tindall, Roger S. Rittmaster,