Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3879488 | The Journal of Urology | 2006 | 7 Pages |
Abstract
In muscle invasive (pT2) bladder cancer treated with radical cystectomy there is a higher risk of lymph node positive disease in deep muscle (pT2b) vs superficial (pT2a) invasion. However, no apparent difference was observed in recurrence-free survival between pT2a (superficial) vs pT2b (deep) muscle invasive tumors when controlling for lymph node status. Recurrence-free survival is significantly improved in patients with pT2 lymph node negative tumors compared to survival in those with pT2 lymph node positive tumors. Patients with muscle invasive (pT2), lymph node negative tumors have excellent clinical outcomes following cystectomy, while those with muscle invasive (pT2), lymph node positive tumors have higher recurrence rates and should be considered for adjuvant treatment protocols.
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Authors
R. James Yu, John P. Stein, Jie Cai, Gus Miranda, Susan Groshen, Donald G. Skinner,