| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3883256 | Kidney International | 2011 | 4 Pages |
Abstract
Ischemia/reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) that is associated with a patient mortality of up to 50%. Currently there are not effective pharmacologic therapies for AKI. This Commentary highlights recent evidence indicating that 20-HETE plays an important role in IRI and that drugs that target this pathway have potential as therapeutic agents for AKI.
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Authors
Richard J. Roman, Talha Akbulut, Frank Park, Kevin R. Regner,