| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3884049 | Kidney International | 2011 | 4 Pages |
Abstract
MicroRNAs are short noncoding RNAs that usually reduce translation of messenger RNAs. Changes in microRNA-192 (miR-192) are reported in states of renal fibrosis. New evidence supports a role for miR-192 and its target miR-200b/c in transforming growth factor-β1 regulation of its own expression and that of collagens in mesangial cells, with a possible role in diabetic nephropathy. As there is controversy on the role of these microRNAs in diabetic nephropathy, more work is needed.
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Authors
Balakuntalam S. Kasinath, Denis Feliers,