| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3884747 | Kidney International | 2010 | 4 Pages |
Abstract
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is a pleiotropic cascade essential to cytokine and growth hormone receptor signaling. Signaling through the JAK/STAT pathway is important for the kidney's response to injury in disease. Pang et al. confirm that activation of STAT3 mediates renal fibrosis in the unilateral ureteral obstruction experimental model.
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Authors
Peter Y. Chuang, John C. He,