Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3886309 | Kidney International | 2007 | 6 Pages |
Abstract
How do infections trigger or aggravate renal pathology? The discovery of the toll-like receptors, and more recently, the retinoic-acid-inducible protein-like helicases and the nucleotide-binding oligomerization domain-like receptors may offer new concepts to answer this question. Common pathogen-associated molecules are recognized by these receptors in several cellular compartments of immune cells and non-immune cells inside the kidney. This article summarizes ligand–receptor interactions and their known or potential significance in kidney diseases.
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Authors
H.-J. Anders,