Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3896829 | Seminars in Nephrology | 2010 | 18 Pages |
Abstract
SummaryThis review provides an overview of the current understanding of the biology of monocytes and macrophages. It focuses on four rapidly advancing areas that underpin recent conceptual advances, namely: (1) the bone marrow origins of monocytes and macrophages, (2) monocyte heterogeneity, (3) the early inflammatory consequences of tissue injury, and (4) current concepts of macrophage activation and their limitations.
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Authors
Andrew J. Rees,