| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3896889 | Seminars in Nephrology | 2012 | 8 Pages |
Abstract
TGF-β is well known to play a critical role in diabetic kidney disease, and ongoing clinical studies are testing the potential therapeutic promise of inhibiting TGF-β production and action. An aspect of TGF-β action that has not received much attention is its potential role in explaining sex-related proclivity for kidney disease. In this review, we discuss recent studies linking TGF-β signaling to sex-related effects in diabetic kidney disease and suggest targets for future studies.
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Authors
Maggie K. PhD, Young H. PhD, Kumar MD,