Urogenital Manifestations of Metastatic Crohn's Disease in Children: Case Series and Review of the Literature

Although cutaneous manifestations are the most common extraintestinal manifestation of inflammatory bowel disease, metastatic Crohn's disease (MCD) is rare. MCD is defined as the presence of noncaseating granulomatous inflammation and perivascular infiltrate in the cutaneous tissue that is noncontiguous to the gastrointestinal tract. MCD rarely involves the genitourinary tract in children. When it does, it can present as external genitalia swelling, erythema, plaques, or ulcerations. Here we present three pediatric cases of MCD involving the genitourinary tract.In addition to discussion of the presented cases, we have reviewed the literature on the genitourinary presentation of MCD in the pediatric population.