Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3899162 | Urology | 2013 | 7 Pages |
Abstract
This study supports the concept that β3-AR agonists inhibit nerve-evoked contractions in human DSM. We have further revealed that BK channels play a critical role in BRL37344-mediated relaxation of nerve-evoked contractions in human DSM. The study suggests that in addition to β3-ARs, BK channels may also represent promising pharmacologic targets in the treatment of urinary bladder dysfunction.
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Authors
Serge A.Y. Afeli, Eric S. Rovner, Georgi V. Petkov,