| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3899165 | Urology | 2013 | 6 Pages |
Abstract
Imatinib caused HCC smooth muscle relaxation in vitro mediated by nitric oxide/guanosine monophosphate signaling, involving the large-conductance Ca(2+)-activated K(+)-channels (BK(Ca)) or by inhibiting the upregulated PTK pathway. These results suggest that imatinib may also benefit erectile dysfunction patients who are not responsive to phosphodiesterase-5 inhibitors.
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Authors
Serap Gur, Suresh C. Sikka, Asim B. Abdel-Mageed, Zakaria Y. Abd Elmageed, Bashir Rezk, Edward Pankey, Philip J. Kadowitz, Wayne J.G. Hellstrom,