Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3901077 | Urology | 2011 | 5 Pages |
Abstract
The complete loss of SMARCB1/INI1 immunoexpression was found in 15% of CDC. No differences were found between the SMARCB1/INI1 positive and negative cases regarding the clinicopathologic and outcome features. Our results suggest that some CDC cases might be associated with genetic alterations involving the SMARCB1/INI1 gene. In addition, SMARCB1/INI1 immunoexpression seems to be of limited value in the differential diagnosis of CDC versus renal medullary carcinoma, although these results require additional validation.
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Authors
Hillary Elwood, Alcides Chaux, Luciana Schultz, Peter B. Illei, Dilek E. Baydar, Athanase Billis, Rajni Sharma, Pedram Argani, Jonathan I. Epstein, George J. Netto,