| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3901283 | Urology | 2011 | 7 Pages |
Abstract
Our results suggest that short hairpin RNA-TGF-β1 plasmid could prevent the fibrosis of renal allografts. The mechanism might be associated with its effects of downregulating phosphorylated Smad3 and upregulating phosphorylated Smad7, leading to the suppression of epithelial-myofibroblast transdifferentiation and extracellular matrix synthesis.
Related Topics
Health Sciences
Medicine and Dentistry
Nephrology
Authors
Zhikang Yin, Yuguo Xia, Chunli Luo, Jiamo Zhang, Yunfeng He, Xiaohou Wu,