Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3901440 | Urology | 2012 | 6 Pages |
Abstract
Our results suggest that the M2 mAChR subtype plays an important role in bladder afferent activation that enhances detrusor overactivity in SCI rats. However, because mAChR antagonists alone did not affect any cystometric parameters, the muscarinic mechanism controlling bladder afferent activity might not be involved in the emergence of detrusor overactivity in SCI.
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Authors
Yoshihiro Matsumoto, Minoru Miyazato, Hitoshi Yokoyama, Masafumi Kita, Yoshihiko Hirao, Michael B. Chancellor, Naoki Yoshimura,