| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3902669 | Urology | 2011 | 7 Pages |
Abstract
The urothelium with the lamina propria exhibits a spontaneous contractile activity that is increased during stretch. The mechanism appears to involve endogenous acetylcholine release acting on M3 muscarinic receptors. Anticholinergic drugs used clinically depress the responses of these tissues, and this mechanism might represent an additional site of action for these drugs in the treatment of bladder overactivity.
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Authors
Christian Moro, Jumpei Uchiyama, Russ Chess-Williams,