| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3904424 | Urology | 2008 | 5 Pages |
Abstract
4-Hydroxynonenal affects pig bladder contractility. L-type calcium channels and or the contractile system of the bladder muscle are susceptible to HNE-mediated damage. The cholinergic nerves and the muscarinic receptor signaling system remain largely unaffected. The effects of HNE are most likely mediated via alkylation of sulfhydryl groups.
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Authors
Rik de Jongh, Guido R.M.M. Haenen, Gommert A. van Koeveringe, Miriam Dambros, Philip E.V. van Kerrebroeck,