| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3904536 | Urology | 2010 | 7 Pages |
Abstract
The colocalization of smooth muscle α-actin and PDE4 with cAK, as well as the results from the organ bath experiments, provide further evidence for a pivotal role of the cAMP-dependent signaling in the regulation of prostate smooth muscle contractility. Compounds interacting with the cAMP/cAK pathway might represent a new therapeutic avenue to treat symptoms of benign prostatic hyperplasia and lower urinary tract symptomatology.
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Authors
Eginhard Waldkirch, Stefan Ãckert, Katja Sigl, Kristina Langnaese, Karin Richter, Christian G. Stief, Markus A. Kuczyk, Petter Hedlund,