| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3908787 | The Breast | 2013 | 12 Pages |
Abstract
Gene expression profiling tests are used in an attempt to determine the right treatment for the right person with early-stage breast cancer that may have spread to nearby lymph nodes but not to distant parts of the body. These new diagnostic approaches are designed to spare people who do not need additional treatment (adjuvant therapy) the side effects of unnecessary treatment, and allow people who may benefit from adjuvant therapy to receive it. In the present review we discuss in detail the major diagnostic tests available such as MammaPrint dx, Oncotype dx, PAM50, Mammostrat, IHC4, MapQuant DX, Theros-Breast Cancer Gene Expression Ratio Assay, and their potential clinical applications.
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Authors
Grazia Arpino, Daniele Generali, Anna Sapino, Lucia Del Matro, Antonio Frassoldati, Michelino de Laurentis, Paolo Pronzato, Giorgio Mustacchi, Marina Cazzaniga, Sabino De Placido, Pierfranco Conte, Mariarosa Cappelletti, Vanessa Zanoni, Andrea Antonelli,