Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3917507 | Early Human Development | 2009 | 4 Pages |
ObjectiveTo study the clinical values of positron emission tomography (PET) in preterm and term newborn infants through observing brain glucose metabolism by 18F-fluorodeoxyglucose (18F-FDG) PET.MethodTo observe the brain 18F-FDG PET imaging in 9 term and 7 preterm newborn infants in the same condition after administration of 0.1 mCi/kg 18F-FDG.ResultThe brain 18F-FDG PET imaging showed that the uptake of 18F-FDG was relatively more in the thalamus, and less in the cerebral cortex in preterm and term newborn infants. The uptake of 18F-FDG of cerebral cortex in preterm infants was less than that in term infants, so the structure of brain 18F-FDG PET imaging was a little fainter in preterm neonates as compared with that in term newborns.Conclusion18F-FDG PET imaging could show different glucose metabolisms of brain in preterm and term infants. Brain 18F-FDG PET imaging might be a useful tool for estimating the brain function in newborn infants, and its clinical values need further investigation.