Article ID Journal Published Year Pages File Type
3923512 European Urology 2006 8 Pages PDF
Abstract

ObjectiveReview management of bacillus Calmette-Guérin (BCG) failures in superficial bladder cancer.MethodSearch of published literature and meeting abstracts.ResultsPatients in whom BCG fails are not a uniform group. Failure cannot be predicted but high-risk patients can be identified. In case of failure and progression the outcome is bad. Conservative but investigative alternatives are BCG/interferon-α, intravesical hyperthermia/chemotherapy, or photodynamic therapy. Standard treatment in failing patients remains cystoprostatectomy.ConclusionBCG failures need careful and individualized therapy in experienced hands.

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