2005 Update on Pathology of Prostate Biopsies with Cancer

ObjectiveTo review the diagnostic and prognostic importance of pathologic findings in prostate biopsies.Materials and ResultsWhile the primary goal of the biopsy is to diagnose prostatic adenocarcinoma, once carcinoma is detected, information regarding the type, amount, and grade of cancer forms the cornerstone for contemporary management of the patient and for assessment of the potential for local cure and the risk for distant metastasis.ConclusionsThe novelty of this 2005 update is represented by a detailed morphologic and immunohistochemical description of prostatic adenocarcinoma features in biopsies.