Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3928261 | European Urology | 2009 | 4 Pages |
Abstract
The authors present the first case report of complete histologic remission after neoadjuvant sunitinib treatment on primary renal tumour and vena cava thrombus. A 78-yr-old woman with an Eastern Cooperative Oncology Group (ECOG) score of 0 presented with a T3b renal tumour. She refused surgical treatment but agreed to percutaneous biopsy and medical treatment. A Fuhrman III renal cell carcinoma was histologically confirmed on percutaneous biopsy, and sunitinib treatment was administered over 6 mo. A significant objective response was observed for tumour size and thrombus. The patient finally accepted surgical treatment. Pathologic examination concluded with a complete response of primary tumour and thrombus.
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Authors
Grégoire Robert, Grégoire Gabbay, Raphaël Bram, Hervé Wallerand, Colette Deminière, François Cornelis, Jean-Christophe Bernhard, Alain Ravaud, Philippe Ballanger,