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Peroxynitrite affects the cumulus cell defense of metaphase II mouse oocytes leading to disruption of the spindle structure in vitro

Article ID Journal Published Year Pages File Type
3931640 Fertility and Sterility 2013 8 Pages PDF
Abstract
ONOO− affects the viability of cumulus cells and the oocyte spindle structure in a dose-dependent manner. Collectively, these effects compromise oocyte quality, which may lead to female infertility.
Keywords
Oxidative stresscumulus cellsPeroxynitriteoocyte qualityReactive oxygen species
Related Topics
Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
Preview
Peroxynitrite affects the cumulus cell defense of metaphase II mouse oocytes leading to disruption of the spindle structure in vitro
Authors
Jashoman M.D., Faten M.D., Dhiman Ph.D., Ghassan M. Ph.D., Jing Ph.D., Michael P. M.D., Husam M. Ph.D.,
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Journal
Fertility and Sterility
Journal: Fertility and Sterility
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