Article ID Journal Published Year Pages File Type
3931956 Fertility and Sterility 2012 8 Pages PDF
Abstract
TGF-β3-induced profibrotic response in fibroid cells is mediated by Smad-dependent and Smad-independent PI3K/Akt/mTOR pathways. 2ME2 inhibits TGF-β3 profibrotic effects in huLM cells by ameliorating both Smad-dependent and Smad-independent signaling pathways.
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Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
Preview
2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells
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