Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3932051 | Fertility and Sterility | 2011 | 7 Pages |
Abstract
EGF stimulates DNA synthesis and polyploidization in leiomyomal SMCs through transient activation of the EGFR-MAPK pathway. Given that polyploidization plays a role in tumorigenesis, our results shed new light on the pathogenesis of human uterine leiomyoma.
Keywords
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Authors
Yuanyuan M.Sc., Hao Ph.D., Ruijuan M.Sc., Lihua M.Sc., Yingjun M.D., Ph.D., Wanjun M.D., Xiang D. M.D., Ph.D., Yu M.D., Ph.D., Xi-Long M.D., Ph.D.,