Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3932224 | Fertility and Sterility | 2011 | 4 Pages |
Abstract
To examine putative associations between zona pellucida (ZP) anomalies and sequence variations in genes expressing structural ZP glycoprotein components, sequence data of 31 volunteers participating in IVF treatments were obtained and analyzed together with morphologic data of the respective oocytes. Our results suggest that some of the most frequent zona anomalies may be at least partly explained by sequence variations in genes expressing the four human ZP proteins, especially those in ZP2 and ZP3.
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Authors
Reeta-Maria Pökkylä, Jouni Tapani Lakkakorpi, Sinikka Helena Nuojua-Huttunen, Juha Samuli Tapanainen,