Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3932246 | Fertility and Sterility | 2011 | 4 Pages |
Abstract
In this study, the sperm protein profile was compared between fertile and infertile men using 2-dimensional gel electrophoresis, liquid chromatography mass spectrometer analysis, and matrix-assisted laser desorption ionization-time-of-flight-mass spectrometry. Four unique proteins, semenogelin II precursor, prolactin-induced protein, clusterin isoform 1, and prostate-specific antigen isoform 1 preproprotein, were predominantly present in the semen of healthy men; however, semenogelin II precursor and clusterin isoform 1 were not seen in the semen of infertile men, suggesting unique differences in the spermatozoa protein profiles of fertile and infertile men.
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Authors
Stetson Thacker, Satya P. Yadav, Rakesh K. Sharma, Anthony Kashou, Belinda Willard, Dongmei Zhang, Ashok Agarwal,