| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3932675 | Fertility and Sterility | 2011 | 4 Pages |
Abstract
Expression of the pluripotency factors SOX-2, OCT-4, KLF-4, and NANOG was analyzed by quantitative real-time polymerase chain reaction, immunohistochemistry, and immunofluorescence microscopy in the endometrium, myometrium, and endometriotic tissue of 36 patients. Aberrant expression of SOX-2 may indicate a stem cell origin of endometriosis, whereas the presence of all progenitor markers in endometrial tissue marks the endometrium as a potential source for induced pluripotent stem cell generation.
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Authors
Martin Götte, Maria Wolf, Annette Staebler, Olaf Buchweitz, Ludwig Kiesel, Andreas N. Schüring,